Acque termali per uso ricreativo: panoramica sulle normative internazionali

Spa facilities used for recreational purposes are widely used in Europe and around the world. The benefits of such environments are referenced, although the chemical mechanisms of these properties are still unclear. The biological and chemical characteristics of these waters do not allow standard disinfection treatments. An overview of European and international laws and regulations has highlighted the gaps on this subject.AL amyloidosis is a result of the clonal plasma cell disorder. It is the most common and severe form of systemic amyloidosis. Amyloid deposits containing free light chains infiltrate the tissues and cause their dysfunction and failure. Amyloidosis could be also divided into localized and systemic forms. Patients with AL amyloidosis not only have an hematologic malignancy, but also present progressive dysfunctions in several organs. Cardiac and renal dysfunction is a common alteration in AL amyloidosis. Lp(a) lipoprotein is a low-density lipoprotein particle in which apolipoprotein B-100 is linked by a single interchain disulfide bridge to a unique glycoprotein, apoprotein(a). For the first time we describe increased levels of lipoprotein(a) in patients affected by AL amyloidosis. The increased level of Lp(a) can exert a pivotal role in the variegated vascular pathology featured in AL amyloidosis.

Impianti termali impiegati a scopo ricreativo sono ampiamente diffusi in Europa e nel resto del mondo. I benefici di tali ambienti sono oggi ampiamente referenziati, pur non essendo ancora noti i meccanismi chimici di tali proprietà. Le caratteristiche biologiche e chimiche di tali acque ne impediscono il trattamento con metodi di disinfezione standard. Una panoramica sulle leggi e normative europee ed internazionali ha messo in luce le lacune su tale argomento.